Familial transmission of a chromosomal translocation t(2q+;Cp-).

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Familial transmission of a chromosomal translocation t(2q+;Cp-).

Reciprocal translocations involving duplications of different regions of chromosomes of group C have been reported in patients with multiple congenital malformations. Some of these cases died at 2 or 3 months of age (de Grouchy et al., 1967a, b; Gray et al., 1966). Others were discovered at ages ranging from 12 months to 12 years (Edwards et al., 1962; Rohde and Catz, 1964; de Grouchy and Canet...

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A Chromosomal Translocation Causing Overproduction

The CYC7-1 mutation in the yeast Saccharomyces cereuisiae causes the production of approximately 30 times the normal amount of iso-2-cytochrome c. Genetic analysis established that the CYC7-I mutation is a reciprocal translocation involving the left arm of chromosome V and the right arm of chromosome XVZ. The chromosome V arm was broken adjacent to the gene CYC7, which determines the primary st...

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Familial translocation t(9;16).

We report a female with a deletion of 9p and concomitant duplication of 16q [46,XX,-9,+der(9),t(9;16)(p24;q13)]. Parental chromosome analysis showed a balanced maternal translocation [46,XX,t(9;16)(p24;q13)]. Three other cases of translocations involving chromosomes 9 and 16 have been reported, one of them with identical breakpoints. A review of published reports of deletion 9p and duplication ...

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Prenatal Diagnosis of Triploidy in Fetus with Unexpected Chromosomal Translocation of Maternal Origin

Triploidy is a lethal chromosomal abnormality. Foetuses with triploid condition have a tendency to die in early conception and very few survive to term. In this study, we report the prenatal diagnosis of fetal triploidy with unexpected chromosomal translocation. A 27 years old women was referred to our clinical cytogenetic department due to history of previous conceptus with intrauterine growth...

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The prevalence of chromosomal translocation t (1; 4) (p21; p14) in Iranian patients with mental disability

Introduction: Intellectual disability or intellectual retardation is a condition in which total mental functioning is distinctively below average and there are disabilities in adaptive behaviors during growth. According to the definition of American Mental Disability Community in 1992 a person is considered intellectually disabled if he or she has an IQ (intelligence quotient) of less than 70...

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ژورنال

عنوان ژورنال: Journal of Medical Genetics

سال: 1969

ISSN: 1468-6244

DOI: 10.1136/jmg.6.2.174